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Page 1
A call to action for translational sciences in COVID-19 and future pandemics.
Nat Rev Drug Discov. 2022 Mar;21(3):165-166. doi: 10.1038/d41573-022-00020-6.
Nat Rev Drug Discov. 2022.
PMID: 35091700
No abstract available.
Simple, chemoselective hydrogenation with thermodynamic stereocontrol.
Iwasaki K, Wan KK, Oppedisano A, Crossley SW, Shenvi RA.
Iwasaki K, et al. Among authors: wan kk.
J Am Chem Soc. 2014 Jan 29;136(4):1300-3. doi: 10.1021/ja412342g. Epub 2014 Jan 15.
J Am Chem Soc. 2014.
PMID: 24428640
Free PMC article.
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Nitrosopurines en route to potently cytotoxic asmarines.
Wan KK, Iwasaki K, Umotoy JC, Wolan DW, Shenvi RA.
Wan KK, et al.
Angew Chem Int Ed Engl. 2015 Feb 16;54(8):2410-5. doi: 10.1002/anie.201411493. Epub 2015 Jan 7.
Angew Chem Int Ed Engl. 2015.
PMID: 25580910
Free PMC article.
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Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations.
Sung K, Kurowski A, Lansiquot C, Wan KK, Patnaik S, Walsh MJ, Lazarus MB.
Sung K, et al. Among authors: wan kk.
ACS Chem Biol. 2022 Dec 16;17(12):3290-3297. doi: 10.1021/acschembio.2c00710. Epub 2022 Dec 5.
ACS Chem Biol. 2022.
PMID: 36469692
Free PMC article.
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Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists.
Patnaik S, Basu D, Southall N, Dehdashti S, Wan KK, Zheng W, Ferrer M, Taylor M, Engel DA, Marugan JJ.
Patnaik S, et al. Among authors: wan kk.
Bioorg Med Chem Lett. 2019 May 1;29(9):1113-1119. doi: 10.1016/j.bmcl.2019.02.027. Epub 2019 Feb 26.
Bioorg Med Chem Lett. 2019.
PMID: 30852083
Free PMC article.
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Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.
Kearney SE, et al. Among authors: wan kk.
ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.
ACS Cent Sci. 2018.
PMID: 30648156
Free PMC article.
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The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.
Caffall ZF, Wilkes BJ, Hernández-Martinez R, Rittiner JE, Fox JT, Wan KK, Shipman MK, Titus SA, Zhang YQ, Patnaik S, Hall MD, Boxer MB, Shen M, Li Z, Vaillancourt DE, Calakos N.
Caffall ZF, et al. Among authors: wan kk.
Sci Transl Med. 2021 Aug 18;13(607):eabd3904. doi: 10.1126/scitranslmed.abd3904.
Sci Transl Med. 2021.
PMID: 34408078
Free PMC article.
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